Despite the initial response, all patients with epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC) eventually develop acquired resistance to EGFR tyrosine kinase inhibitors (TKIs).The EGFR-T790M secondary mutation is responsible for half of acquired resistance cases, while MET amplification has been associated with ac

The purpose of this community service is to provide knowledge about managing plastic waste through Reduce, Reuse, and Recycle (3R).Ecobrick is one of the recycling efforts to minimize the amount of plastic waste movements, by providing knowledge and Stationery skills to PAUD Sukun teachers, South Maitara Village, Tidore Islands City in utilizing pl

The essay analyzes the adjustment of the ideas of classical liberalism in Latin America in the nineteenth century.Within a historiographical, hermeneutical, and analytical methodology of some cases that exemplify political and economic ideas, a general conclusion has been SLEEP TIGHT reached: the ideas of classical liberalism became a superficial m

This study is aimed to evaluate the adaptive mechanism in two common bean (Phaseolus vulgaris L.) cultivars, cv.Bronco and cv.Paulista subjected to different concentrations of NaCl (0, 25, ACCESSORIES SCARVES 50 and 75 mM).Salt treatments resulted in a significant decrease in the fresh and dry biomasses of shoots and roots as well as leaf relative

MAPK-activated protein kinase 2 (MK2), a direct substrate of p38 MAPK, plays key roles in multiple physiological functions in mitosis.Here, we Placemats show for the first time the unique distribution pattern of MK2 in meiosis.Phospho-MK2 was localized on bipolar spindle minus ends and along the interstitial axes of homologous chromosomes extending